import numpy as np import pandas as pd df = pd.DataFrame({'List1':[1,2,3, 4,5,5,11,4],'List 2':[3,5,6,8,9,3,4,9]}, columns=['List1', 'List 2']) #df.to_excel("list1.xlsx", header=True, index=False) df['Intersect']=pd.DataFrame( np.intersect1d(df['List1'], df['List 2'])) #unique common in both df['commonin1']=df['List1'][ np.in1d(df['List1'], df['List 2'])] #non unique common items of list 1 df['commonin2']=df['List 2'][np.in1d(df['List 2'], df['List1'])] #non unique common items of list 2 df['1not2']=pd.DataFrame(np. setdiff1d(df['List1'], df['List 2'])) #in list1 but not in list 2 df['2not1']=pd.DataFrame(np. setdiff1d(df['List 2'], df['List1'])) #in list 2 but not in list1 df['1not2NU']=df['List1'][~np. in1d(df['List1'], df['List 2'])] #in list1 but not in list 2 non unique d